Acronym

CIS

Carcinoma in situ

A pre-invasive epithelial malignancy that has not breached the basement membrane.

What it means

A pre-invasive epithelial malignancy that has not breached the basement membrane.

Clinical context

CIS is commonly used in Histopathology, Oncology. The exact meaning can depend on specialty, region and local documentation practice.

Learning note

Use the full term when clarity matters, especially in formal assignments, prescriptions, handover and patient-facing communication.